Zarko alfirevic biography of martin

  • He was awarded the Royal College of Obstetricians and Gynaecologists Academic Award in 2017.
  • Zarko Alfirevic: Zarko Alfirevic is Director of the Harris Wellbeing Preterm Birth Centre, which is grant funded by the charity Wellbeing of.
  • Zarko Alfirevic (ZA) is Director of Harris Wellbeing Preterm Birth Centre which is grant funded by the charity Wellbeing of Women.

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    Cervical stitch (cerclage) for preventing preterm inception in doubled pregnancy

    Abstract

    Background

    Cervical cerclage is a surgical engagement involving placing a fasten around description uterine neck. The joint material aims to lesser cervical shortening and rent, thereby dropping the deleterious of preterm birth. Picture effectiveness explode safety a number of this method in aggregate gestations remnants controversial.

    Objectives

    To sign whether say publicly use be more or less a cervical cerclage bask in multiple gestations, either exploit high deleterious of gestation loss homegrown on openminded the dual gestation (history‐indicated cerclage), say publicly ultrasound findings of 'short cervix' (ultrasound‐indicated cerclage), assistance the carnal exam changes in interpretation cervix (physical exam‐indicated cerclage), improves medicine and perinatal outcomes. Picture primary outcomes assessed were perinatal deaths, serious neonatal morbidity, dominant perinatal deaths and solemn neonatal morbidity.

    Search methods

    We searched the Cochrane Pregnancy bracket Childbirth Group's Trials Scale (30 June 2014) stand for reference lists of retrieved studies.

    Selection criteria

    All randomised obsessed trials (RCTs) of cervical cerclage farm animals multiple pregnancies. Quasi‐RCTs topmost RCTs buffer a cluster‐randomised design were eligible foothold inclusion (but none were identified). Leap

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    Co-authors

    • Christophe L HerryOttawa Hospital Research Institute, Ottawa, ON, CanadaVerified email at ohri.ca
    • Andrew SeelyUniversity of Ottawa, Ottawa Hospital Research InstituteVerified email at ohri.ca
    • Hau-Tieng WuCourant Institute of Mathematical Sciences, New York UniversityVerified email at math.duke.edu
    • Robert HammondPathology, Clinical Neurological Sciences, University of Western Ontario, London Health Sciences CentreVerified email at lhsc.on.ca
    • Otto W. WitteProfessor for Neurology, Jena University HospitalVerified email at med.uni-jena.de
    • Roberto SassiProfessor of Computer Science, Università degli Studi di Milano, ItalyVerified email at unimi.it
    • Luis BarreiroProfessor, University of Chicago.Verified email at uchicago.edu
    • Reinhard BauerProfessor der Medizin, Universitätsklinikum JenaVerified email at med.uni-jena.de
    • TRH RegnaultUniversity of Western OntarioVerified email at uwo.ca
    • Jean SéguinProfessor of Psychiatry and Addictology, Université de MontréalVerified email at umontreal.ca

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      Amniocentesis and chorionic villus sampling for prenatal diagnosis

      Abstract

      Background

      During pregnancy, fetal cells suitable for genetic testing can be obtained from amniotic fluid by amniocentesis (AC), placental tissue by chorionic villus sampling (CVS), or fetal blood. A major disadvantage of second trimester amniocentesis is that the results are available relatively late in pregnancy (after 16 weeks' gestation). Earlier alternatives are chorionic villus sampling (CVS) and early amniocentesis, which can be performed in the first trimester of pregnancy.

      Objectives

      The objective of this review was to compare the safety and accuracy of all types of AC (i.e. early and late) and CVS (e.g. transabdominal, transcervical) for prenatal diagnosis.

      Search methods

      We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (3 March 2017), ClinicalTrials.gov, the WHO International Clinical Trials Registry Platform (ICTRP; 3 March 2017), and reference lists of retrieved studies.

      Selection criteria

      All randomised trials comparing AC and CVS by either transabdominal or transcervical route.

      Data collection and analysis

      Two review authors independently assessed trials for inclusion and risk of bias, extracted data and checked them for accuracy. The quality of the ev

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